- Joint pain and swelling, especially in the smaller joints of the hands and feet
- Joint and muscle aching or stiffness after sleep or long periods of rest
- Loss of motion in the affected joints
- Loss of strength in muscles attached to the affected joints
- Severe fatigue during flare-ups
- General sense of not feeling well
- Deformity of the joints over time
Unlike osteoarthritis, which affects only the bones and joints, rheumatoid arthritis can also cause inflammation of tear glands, salivary glands, the lining of the heart and lungs, the lungs themselves, and in rare cases, the blood vessels.